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household with an approved flea protection product. Administer comfortis with food for maximum effectiveness. Comfortis kills fleas before they can lay eggs. In a field study conducted in households with existing flea infestations in dogs, flea count reductions.9 were observed one month after the first treatment and.9 after three monthly treatments with Comfortis.4. In a separate well-controlled laboratory study, comfortis demonstrated 100 effectiveness on the first day following treatment and 90 effectiveness on Day. Insects treated with spinosad show involuntary muscle contractions and tremors resulting from activation of motor neurons. Read More, preventing Periodontal Disease in Dogs and Cats.

The most frequently reported adverse reaction in cats was vomiting. Hematology and clinical chemistry values were compared pre- and post-study and were unremarkable. Comfortis should be administered at monthly intervals.

Each tablet size is available in color-coded packages of 6 tablets. If vomiting occurs within an hour of administration, redose with another full dose. Adverse Reactions, in a well-controlled US field study, which included a total of 211 cats (139 treated with comfortis and 72 treated with an active topical control once a month for 3 treatments no serious adverse reactions were attributed to the administration of comfortis. The administration of comfortis was not associated with any clinically significant, gross necropsy or histopathological changes. In a well-controlled field study, comfortis was administered safely in conjunction with other frequently used veterinary products, including tapeworm anthelmintics, antibiotics, and an approved heartworm preventative containing ivermectin. Spinosad contains two major factors, spinosyn A and spinosyn D, derived from the naturally occurring bacterium, Saccharopolyspora spinosa. Spinosyn A and spinosyn D have the chemical compositions 2 - (6 - deoxy - 2,3,4 - tri - O - methyl - - L - mannopyranosyl)oxy dimethylamino) - tetrahydro - 6 - methyl - 2H - pyran - 2 - yloxy - 9 - ethyl. When you want to get rid of fleas, choose Comfortis. Nada #141-277, Approved by the FDA Manufactured for: Elanco US Inc., Greenfield, IN 46140 m Elanco, Comfortis and the diagonal bar are trademarks owned or licensed by Eli Lilly and Company, its subsidiaries or affiliates.

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