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to the following aspects of sexual function: 1) sex drive, 2) ease of arousal, 3) ability to achieve erection (men) or lubrication (women 4) ease of reaching orgasm, and 5) orgasm satisfaction. Call your healthcare provider between visits as needed, especially if you have concerns about symptoms. Results from a single-dose pharmacokinetic study in elderly ( 65 years old). No effect of food on the pharmacokinetics was observed. Negligible amounts of unchanged vortioxetine were excreted in the urine up to 48 hours. The following symptoms anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia (psychomotor restlessness hypomania, and mania have been reported in adult and pediatric patients being treated with antidepressants for MDD as well as for other indications, both psychiatric and nonpsychiatric. Potential for Other Drugs to Affect Brintellix Reduce Brintellix dose by half when a strong CYP2D6 inhibitor (e.g., bupropion, fluoxetine, paroxetine, quinidine) is coadministered. It should be noted that Brintellix is not approved for use in treating bipolar depression. Common Trintellix side effects may include: nausea; vision changes; occasional vomiting; or constipation. Ask your healthcare provider or pharmacist if you are not sure if you take an maoi, including the antibiotic linezolid. Do not take extra medicine to make up the missed dose.

The concomitant use of Brintellix with maois intended to treat psychiatric disorders is contraindicated. Barcode Package Display Panel-20 mg 30 count Bottle NDC Tablets Rx Only Brintellix vortioxetine tablets 20 mg* Attention: Dispense with the accompanying Medication Guide. Serotonin Syndrome Caution patients about the risk of serotonin syndrome, particularly with the concomitant use of Brintellix and triptans, tricyclic antidepressants, fentanyl, Lithium, tramadol, tryptophan supplements, and.

Brintellix Dosage and Administration. May 2, 2016 Takeda Pharmaceuticals.S.A., Inc. And Lundbeck announced that Brintellix (vortioxetine) will be marketed in the United States under the new name Trintellix (vortioxetine) effective June 2016.

Clinical Studies The efficacy of Brintellix in treatment for MDD was established in six 6 to 8 week randomized, double-blind, placebo-controlled, fixed-dose studies (including one study in the elderly) and one maintenance study in adult inpatients and outpatients who met the Diagnostic and Statistical Manual. The pharmacokinetics of vortioxetine (2.5 mg to 60 mg) are linear and dose-proportional when vortioxetine is administered once daily. By: Lundbeck, Deerfield, IL 60015 Brintellix is a trademark. Patients on Brintellix experienced a statistically significantly longer time to have recurrence of depressive episodes than did patients on placebo. Nausea was more common in females than males.

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